Understanding the role of T-type VGCC and ER-β in Triple-Negative Breast Cancer

Sahu, Chittaranjan and Bhargava, Anamika (2020) Understanding the role of T-type VGCC and ER-β in Triple-Negative Breast Cancer. Masters thesis, Indian Institute of Technology Hyderabad.

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Triple-Negative Breast Cancer (TNBC) doesn’t express Estrogen Receptor-α (ER-α), Progesterone Receptor (PR), and Human Epidermal Growth Receptor (HER 2). Out of the total breast cancers reported, 15-20% are of TNBC type. Out of the overall mortality caused in breast cancer, 50% of the death is caused due to TNBC alone. Due to the absence of these growth receptors, the TNBC cannot be treated using traditional therapies targeting these growth receptors. Therefore it is important to identify new receptors and channels that can be targeted to treat the TNBC.

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IITH Creators:
IITH CreatorsORCiD
Bhargava, Anamikahttp://orcid.org/0000-0002-1048-3427
Item Type: Thesis (Masters)
Uncontrolled Keywords: TNBC, ER-β,T-type VGCC, Proliferation, Migration
Subjects: Others > Biotechnology
Divisions: Department of Biotechnology
Depositing User: . LibTrainee 2021
Date Deposited: 17 Jan 2022 06:16
Last Modified: 17 Jan 2022 06:18
URI: http://raiith.iith.ac.in/id/eprint/9097
Publisher URL:
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