Optical measurements of mechanical resonances in biological tissues via magnetic nanoparticle interrogation

Vasilica, Crecea and Steven, Adie and John, Renu and et al, . (2012) Optical measurements of mechanical resonances in biological tissues via magnetic nanoparticle interrogation. In: American Physical Society (APS) Meeting, 21-25 March 2012, Texas, USA..

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Abstract

We present a real-time phase-resolved optical coherence tomography-based technique that interrogates the mechanical properties of tissue phantoms with different elasticities as well as healthy and cancerous rat tissues, via the interaction of high susceptibility iron oxide nanoparticles that reside inside the samples and an external magnetic field. A chirped magnetic field selects the region of natural resonance in the probed samples as evidenced by scatterer displacements measured with nanometer-level sensitivity. This methodology, entitled magnetomotive optical coherence elastography (MM-OCE), which exploits frequency dependent viscoelastic response in biological media, has potential for detecting tissue pathologies.

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IITH Creators:
IITH CreatorsORCiD
John, Renuhttps://orcid.org/0000-0003-3254-2472
Item Type: Conference or Workshop Item (Paper)
Subjects: Biomedical Engineering
Divisions: Department of Biomedical Engineering
Depositing User: Library Staff
Date Deposited: 18 Sep 2019 05:47
Last Modified: 18 Sep 2019 05:47
URI: http://raiith.iith.ac.in/id/eprint/6310
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