Choroidal Vascularity in Non-arteritic Anterior Ischaemic Optic Neuropathy

Guduru, Abhilash and Abdul Rasheed, Mohammed and Goud, Abhilash and Ashik, Mohamed and Vupparaboina, Kiran Kumar and Chhablani, Jay and Badakere, Akshay and Kekunnaya, Ramesh and Patil-Chhablani, Preeti (2019) Choroidal Vascularity in Non-arteritic Anterior Ischaemic Optic Neuropathy. Neuro-Ophthalmology. pp. 1-5. ISSN 0165-8107

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This study evaluates the peripapillary choroidal vascularity in eyes with non-arteritic anterior ischaemic optic neuropathy (NAION) and compares it with the vascularity of healthy fellow eyes and age-matched subjects. The peripapillary choroidal vascularity index (CVI), a new tool of measurement, was calculated using horizontal swept-source optical coherence tomography scans. CVI was calculated using a previously validated automated algorithm. CVI in NAION and fellow eyes of NAION patients were compared with age-matched eyes of healthy individuals using Kruskal–Wallis test. A total of 20 eyes of 20 patients with acute unilateral NAION with healthy fellow eyes (20 eyes) and 40 eyes of 40 healthy patients were included in the study. The average age of patients with NAION was 56 ± 8 and 55 ± 7 years in age-matched healthy controls. NAION eyes had a significantly lower CVI than age-matched controls in both nasal and temporal areas. NAION nasal CVI was 0.47 ± 0.47 compared to 0.62 ± 0.04 in controls (p < 0.001). NAION temporal CVI was 0.45 ± 0.48 compared to 0.58 ± 0.04 in controls (p < 0.001). Temporal CVI was 0.45 ± 0.48 in NAION eyes and was significantly lower than counterpart healthy fellow eyes 0.48 ± 0.02 (p = 0.007). In conclusion, NAION eyes have significantly reduced vascularity in the peripapillary area. CVI is lower in the nasal and temporal of the optic disc compared to healthy individuals. This may suggest those with smaller CVI are more prone to ischaemia from reduced vascularity resulting in NAION.

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IITH Creators:
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Item Type: Article
Uncontrolled Keywords: Non-arteritic anterior ischaemic optic neuropathy, choroidal vascularity index, peripapillary choroidal vascularity
Subjects: Electrical Engineering
Divisions: Department of Electrical Engineering
Depositing User: Team Library
Date Deposited: 12 Feb 2019 06:30
Last Modified: 12 Feb 2019 06:30
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