Effect of platelet concentration and calcium on Plasma clot absorbance

Susree, Modepalli and Mohan, Anand (2016) Effect of platelet concentration and calcium on Plasma clot absorbance. International Journal of Research in Engineering and Technology, 05 (06). pp. 102-104. ISSN 2321-7308

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Clot structure is greatly influenced by a number of factors in vivo, calcium concentration being one of them. A pilot study with 10 healthy individuals was performed to investigate the effect of added calcium, in combination with plasma platelet concentrati on, on the turbidity of clots. Using a UV - Vis spectrophotometer, absorbance of both platelet - rich and platelet - poor clots was taken at 405 nm, in the presence as well as the absence of added calcium. A 9.93% increase in the maximum absorbance is observed for PRP with added calcium while a 7.68% increase was observed for PPP. Also, PRP clots reported higher absorbance than PPP clots both with (16.48%) and without (14.10%) calcium. It was also observed in parallel that platelet concentration also affe cted turbidity of the clots with & without added calcium.

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IITH Creators:
IITH CreatorsORCiD
Anand, Mohanhttps://orcid.org/0000-0001-7191-4991
Item Type: Article
Uncontrolled Keywords: Calcium, Platelet-Poor Plasma (PPP), Platelet-Rich Plasma (PRP), Thrombin, and Turbidity.
Subjects: Chemical Engineering
Divisions: Department of Chemical Engineering
Depositing User: Team Library
Date Deposited: 21 Dec 2017 09:20
Last Modified: 30 May 2022 08:46
URI: http://raiith.iith.ac.in/id/eprint/3706
Publisher URL:
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