Effect of Wall Flexibility on the Deformation during Flow in a Stenosed Coronary Artery

Kallekar, Laxman and Chinthapenta, Viswanath and Mohan, Anand (2017) Effect of Wall Flexibility on the Deformation during Flow in a Stenosed Coronary Artery. Fluids, 2 (2). pp. 1-10. ISSN 2311-5521

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The effect of varying wall flexibility on the deformation of an artery during steady and pulsatile flow of blood is investigated. The artery geometry is recreated from patient-derived data for a stenosed left coronary artery. Blood flow in the artery is modeled using power-law fluid. The fluid-structure interaction of blood flow on artery wall is simulated using ANSYS 16.2, and the resulting wall deformation is documented. A comparison of wall deformation using flexibility models like Rigid, Linear Elastic, Neo-hookean, Mooney-Rivlin and Holzapfel are obtained for steady flow in the artery. The maximum wall deformation in coronary flow conditions predicted by the Holzapfel model is only around 50% that predicted by the Neo-Hookean model. The flow-induced deformations reported here for patient-derived stenosed coronary artery with physiologically accurate model are the first of its kind. These results help immensely in the planning of angioplasty.

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IITH Creators:
IITH CreatorsORCiD
Chinthapenta, ViswanathUNSPECIFIED
Anand, Mohanhttps://orcid.org/0000-0001-7191-4991
Item Type: Article
Uncontrolled Keywords: fluid-structure interaction (FSI), stenosed artery, steady flow, pulsatile flow, wall deformation, Holzapfel model
Subjects: Chemical Engineering
Divisions: Department of Chemical Engineering
Depositing User: Team Library
Date Deposited: 07 Jun 2017 03:58
Last Modified: 30 May 2022 08:44
URI: http://raiith.iith.ac.in/id/eprint/3200
Publisher URL: https://doi:10.3390/fluids2020016
OA policy: http://www.sherpa.ac.uk/romeo/issn/2311-5521/
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