Chemistry and Biology of Marine Sponge Collagens

Sobha, K and Devarai, Santhosh Kumar (2016) Chemistry and Biology of Marine Sponge Collagens. In: Marine Sponges: Chemicobiological and Biomedical Applications. Springer India, pp. 359-372. ISBN 978-81-322-2792-2

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Collagens are the proteins found in the extracellular matrix of multicellular organisms, from primitive sponges (parazoans) to highly advanced mammals (metazoans). These proteins, classified as the “collagen superfamily,” comprise about 28 members each with at least one triple-helical domain. Collagens deposited in the extracellular matrix (ECM) and connective tissues form supramolecular assemblies and function as structural proteins contributing to mechanical properties, organization, and shape of tissues. They regulate cell proliferation, migration, and differentiation by binding to cognate receptors on the cell surface and triggering signal transduction cascades. Collagens with restricted tissue distribution perform specific biological functions. This chapter envisages the structural and functional characteristics of both invertebrate and vertebrate collagens with a special account of sponge collagens and their significance in tissue engineering.

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IITH Creators:
IITH CreatorsORCiD
Devarai, Santhosh KumarUNSPECIFIED
Item Type: Book Section
Uncontrolled Keywords: Collagen structure, Tissue engineering, Marine sponges, Types of collagen
Subjects: Others > Geosciences
Chemical Engineering > Biochemical Engineering
Divisions: Department of Chemical Engineering
Depositing User: Team Library
Date Deposited: 22 Nov 2016 06:05
Last Modified: 01 Sep 2017 11:26
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