Highly sensitive SAM modified electrospun zinc oxide nanofiber based label free biosensing platform

Paul, B and Prakash, D and Singh, Shiv Govind and Vanjari, Siva Rama Krishna (2015) Highly sensitive SAM modified electrospun zinc oxide nanofiber based label free biosensing platform. In: IEEE, SENSORS, 1-4 Nov. 2015, Busan.

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The present work demonstrates ultrasensitive, label free biosensor platform using Self Assembled Monolayer (SAM) modified Electrospun ZnO nanofibers. The inherent sensing ability of ZnO nanofibers is enhanced by modifying the fibers with 3-mercaptopropionic (MPA) acid. This role of MPA is to generate carboxylic acid (-COOH) group which can easily be functionalized with any protein molecule by a simple, well established crosslinking biochemistry. To synthesize the nanofibers electrospinning technique, a simple, low cost, robust technique, was utilized. The as-synthesized ZnO nanowires were characterized using Field emission-scanning electron microscopy (FE-SEM), Energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD). The performance of sensor was verified with standard Biotin-Streptavidin interaction as model system using Cyclic Voltammetry (CV). The sensor exhibits excellent sensitivity (613 μA/mg ml-1/cm2) within 1 μgml-1-1fgml-1 of streptavidin with lfgml-1 lower detection limit.

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IITH Creators:
IITH CreatorsORCiD
Singh, Shiv Govindhttp://orcid.org/0000-0001-7319-879X
Vanjari, Siva Rama KrishnaUNSPECIFIED
Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: Biosensors, Calcination, Electrodes, II-VI semiconductor materials, Nanobioscience, Yttrium, Zinc oxide
Subjects: Others > Electricity
Others > Electronic imaging & Singal processing
Others > Engineering technology
Divisions: Department of Electrical Engineering
Depositing User: Team Library
Date Deposited: 28 Apr 2016 05:29
Last Modified: 16 Jan 2019 10:45
URI: http://raiith.iith.ac.in/id/eprint/2298
Publisher URL: https://doi.org/10.1109/ICSENS.2015.7370418
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