Concise Three-Step Strategy for the Synthesis of 2-Benzoxepin-3(1H)-ones

Hazra, M and Jonnada, K and G, Satyanarayana (2015) Concise Three-Step Strategy for the Synthesis of 2-Benzoxepin-3(1H)-ones. Synthesis, 47 (9). pp. 1245-1254. ISSN 0039-7881

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A short and efficient method was developed for the synthesis of 2-benzoxepin-3(1H)-ones. The synthetic sequence comprises of initial intermolecular Heck coupling, followed by reduction of the carbonyl functionality of the Heck product and finally base-induced intramolecular condensation. Notably, the final condensation may proceed by an interesting oxy-Michael addition, cycloreversion via double bond isomerization and intramolecular condensation.

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IITH Creators:
IITH CreatorsORCiD
G, SatyanarayanaUNSPECIFIED
Item Type: Article
Additional Information: Supporting information for this article is available online at
Uncontrolled Keywords: palladium catalysis - Heck coupling - reduction - condensation - benzoxepinones
Subjects: ?? sub5.8 ??
Divisions: Department of Chemistry
Depositing User: Team Library
Date Deposited: 07 Apr 2015 05:31
Last Modified: 24 Sep 2015 10:18
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