Khati, V. and Ramachandraiah, H. and Gaudenzi, G. and Pati, Falguni and et al, .
(2021)
A TUNABLE DECELLULARIZED LIVER-BASED HYBRID BIOINK.
In: 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021, 10 October 2021through 14 October 2021, Palm Springs, Virtual.
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Abstract
Decellularized extracellular matrix is a tissue-specific biomaterial that recapitulates the complexity of the inherent tissue environment to elicit cellular response. Here, a multi-material decellularized liver (dLM)-based bioink with gelatin is developed and polyethylene glycol crosslinking is used to enhance the viscoelasticity of the dLM. We evaluated the necessity of a post-printing secondary cross-linker mushroom tyrosinase to improve robustness and long term stability. We further demonstrate it's biocompatibility using liver specific gene analysis of HepG2 cells. © 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.
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| IITH Creators: |
| IITH Creators | ORCiD |
|---|
| Pati, Falguni | http://orcid.org/0000-0002-3588-1800 |
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| Item Type: |
Conference or Workshop Item
(Paper)
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| Uncontrolled Keywords: |
bioink, decellularization, dLM, SVA-PEG-SVA, tyrosinase, viscoelastic |
| Subjects: |
Biomedical Engineering |
| Divisions: |
Department of Biomedical Engineering |
| Depositing User: |
. LibTrainee 2021
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| Date Deposited: |
08 Sep 2022 12:09 |
| Last Modified: |
08 Sep 2022 12:09 |
| URI: |
http://raiith.iith.ac.in/id/eprint/10484 |
| Publisher URL: |
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| Related URLs: |
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