Current commercial dPCR platforms: technology and market review

Tan, Li Ling and Loganathan, Nitin and Agarwalla, Sushama and Yang, Chun and Yuan, Weiyong and Zeng, Jasmine and Wu, Ruige and Wang, Wei and Duraiswamy, Suhanya (2022) Current commercial dPCR platforms: technology and market review. Taylor and Francis Ltd..

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Abstract

Digital polymerase chain reaction (dPCR) technology has provided a new technique for molecular diagnostics, with superior advantages, such as higher sensitivity, precision, and specificity over quantitative real-time PCRs (qPCR). Eight companies have offered commercial dPCR instruments: Fluidigm Corporation, Bio-Rad, RainDance Technologies, Life Technologies, Qiagen, JN MedSys Clarity, Optolane, and Stilla Technologies Naica. This paper discusses the working principle of each offered dPCR device and compares the associated: technical aspects, usability, costs, and current applications of each dPCR device. Lastly, up-and-coming dPCR technologies are also presented, as anticipation of how the dPCR device landscape may likely morph in the next few years. © 2022 Informa UK Limited, trading as Taylor & Francis Group.

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IITH Creators:
IITH CreatorsORCiD
Duraiswamy, Suhanyahttps://orcid.org/0000-0002-1803-5389
Item Type: Other
Uncontrolled Keywords: Digital PCR; equipment; instrument; polymerase chain reaction; QuantStudio; QX100; QX200; real-time PCR
Subjects: Physics > Mechanical and aerospace
Materials Engineering > Materials engineering
Chemical Engineering
Divisions: Department of Chemical Engineering
Department of Material Science Engineering
Department of Mechanical & Aerospace Engineering
Depositing User: . LibTrainee 2021
Date Deposited: 23 Jul 2022 04:06
Last Modified: 23 Jul 2022 04:06
URI: http://raiith.iith.ac.in/id/eprint/9874
Publisher URL: http://doi.org/10.1080/07388551.2022.2037503
OA policy: https://v2.sherpa.ac.uk/id/publication/785
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