Photothermal therapy assisted bioactive nanoprobes for effective cancer theranostics

Pemmaraju, Deepak Bharadwaj and Appidi, Tejaswini and Rengan, Aravind Kumar (2019) Photothermal therapy assisted bioactive nanoprobes for effective cancer theranostics. In: 7th IEEE International Conference on E-Health and Bioengineering, EHB, 21-23 November 2019, StreetIasi, Romania.

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Abstract

Development of smart bioactive materials which can be ideal for cancer therapy is the need of the hour. In the current study, we have entrapped a bioactive hydrophobic plant fraction into a polymeric and liposomal nanoprobes. Various parameters like size, photothermal efficacy, release and therapeutic efficacy in cancer cells were evaluated. We found that both the nanosystem are efficient in terms of the photothermal transduction efficacy. However, the relative cellular internalization and therapeutic efficacy were higher in the case of the polymeric nano probes. Further in-vivo studies can help to translate them as technology-driven active cancer theranostic agents.

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IITH Creators:
IITH CreatorsORCiD
Rengan, Aravind KumarUNSPECIFIED
Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: Bioactive Nanoprobes, Bioavailability, Cancer theranostics, Liposomes, Polymers ,Indexed in Scopus
Subjects: Biomedical Engineering
Divisions: Department of Biomedical Engineering
Depositing User: Team Library
Date Deposited: 27 Feb 2020 06:53
Last Modified: 27 Feb 2020 06:53
URI: http://raiith.iith.ac.in/id/eprint/7481
Publisher URL: http://doi.org/10.1109/EHB47216.2019.8969989
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