Fibrinolysis: Relative Effect of Inhibitors

Susree, Modepalli and Mohan, Anand (2017) Fibrinolysis: Relative Effect of Inhibitors. In: 5 th International Conference on Computational and Mathematical Biomedical Engineering - CMBE, 10–12 April 2017, United States.

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Abstract

The process of fibrinolysis succeeds clot formation in blood plasma. It is imperative that both the complementary processes of clot formation and lysis occur in a regulated manner in order to maintain the integrity of the human vasculature. Regulation of fibrinolysis in the body by constituent fibrinolysis inhibitors or by anti-fibrinoytic drugs is of importance in cases of hypocoagulation and excessive bleeding. This study presents a non-invasive model for understanding the underlying mechanisms in fibrinolysis and its inhibition by α2AP, PAI and TAFI using a mechanistic model.

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IITH Creators:
IITH CreatorsORCiD
Mohan, Anandhttps://orcid.org/0000-0001-7191-4991
Item Type: Conference or Workshop Item (Paper)
Subjects: Chemical Engineering
Divisions: Department of Chemical Engineering
Depositing User: Team Library
Date Deposited: 03 Dec 2019 05:28
Last Modified: 03 Dec 2019 05:28
URI: http://raiith.iith.ac.in/id/eprint/7091
Publisher URL:
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