Acid/Base Mediated Conjugate AdditionAromatization/Rearrangement: Concise Synthesis of Diarylmethanes, Diarylpropanes, 2-Arylindoles and Chromanes

Sreenivas, Kukkamudi and Khan, Faiz Ahmed (2019) Acid/Base Mediated Conjugate AdditionAromatization/Rearrangement: Concise Synthesis of Diarylmethanes, Diarylpropanes, 2-Arylindoles and Chromanes. PhD thesis, Indian institute of technology Hyderabad.

Full text not available from this repository. (Request a copy)

Abstract

In organic synthesis, norbornyl derivatives are one of the most important building blocks for the synthesis of various natural products, unnatural products as well as aesthetically pleasing molecules. In the recent past, we have reported α-diketones from tetrahalo norbornyl derivative by employing the efficient recyclable ruthenium catalytic oxidation (Ru-LDH: RuCl3.3H2O immobilized onto layered double hydroxide, LDH). These α-diketone derivatives are well explored for the synthesis of various natural products as well as pharmaceutically vital substances. They were utilized to synthesize the bridge lactones or bis γ-lactone or diesters by employing alkaline hydrogen peroxide cleavage strategy. In addition, a novel synthesis of functionalized pentenomycins starting from α-diketone derivatives was reported in our group. Moreover, we disclosed a new route for the synthesis of spirocyclic lactams and also a variety of norbornyl α-diketones were transformed into corresponding strained oxa-bridged compounds.

[error in script]
IITH Creators:
IITH CreatorsORCiD
Khan, Faiz AhmedUNSPECIFIED
Item Type: Thesis (PhD)
Uncontrolled Keywords: Cyclohexadienone, 1,6-Conjugate addition, Diarylmethanes, Diarylpropanes, 2-Arylindoles, Chromanes TD1566
Subjects: Chemistry
Divisions: Department of Chemistry
Depositing User: Team Library
Date Deposited: 09 Aug 2019 06:22
Last Modified: 21 Sep 2019 09:56
URI: http://raiith.iith.ac.in/id/eprint/5893
Publisher URL:
Related URLs:

    Actions (login required)

    View Item View Item
    Statistics for RAIITH ePrint 5893 Statistics for this ePrint Item