Bronsted Acid-Mediated Domino One-Pot Dual C–C Bond Formation: Chemoselective Synthesis of Fused Tricyclic Ketones

Pedireddi, Niharika and Ramulu, B V and G, Satyanarayana (2018) Bronsted Acid-Mediated Domino One-Pot Dual C–C Bond Formation: Chemoselective Synthesis of Fused Tricyclic Ketones. ACS Omega, 3 (1). pp. 218-228. ISSN 2470-1343

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Abstract

A chemoselective synthesis of fused novel tricyclic motifs via a facile domino intramolecular cyclization is presented. The strategy enables the formation of dual C–C bond via intramolecular Friedel–Crafts alkylation followed by acylation to accomplish fused tricyclic ketones. Significantly, these fused tricyclic compounds are ubiquitous and constitute major structural cores of natural products.

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IITH Creators:
IITH CreatorsORCiD
G, SatyanarayanaUNSPECIFIED
Item Type: Article
Subjects: Chemistry
Divisions: Department of Chemistry
Depositing User: Team Library
Date Deposited: 17 Jan 2018 04:45
Last Modified: 17 Jan 2018 04:45
URI: http://raiith.iith.ac.in/id/eprint/3729
Publisher URL: https://doi.org/10.1021/acsomega.7b01553
OA policy: http://www.sherpa.ac.uk/romeo/issn/2470-1343/
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