Full - Field Optical Coherence Tomography and Monte Carlo Simulations for Biological Tissues

Dnyandev, Phad Vaibhav (2016) Full - Field Optical Coherence Tomography and Monte Carlo Simulations for Biological Tissues. Masters thesis, Indian Institute of Technology Hyderabad.

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Abstract

Optical Coheren ce Tomography ( OCT) is a n emerging imaging technique that has been successfully demonstrated for non - invasive, non - contact and in - vivo imaging of biological specimen. Over the years, several OCT modifications have been developing so that present OCT system limitations can be overcome thereby extending its applications in various fields. Full - field OCT (FF - OCT) is one of the recent advancement in the OCT. In this thesis, FF - OCT system for imaging of biological tissues is presented. The image reconstr uction of the system is performed using phase stepping methods to produce object images with better computational efficiency. This thesis also explores Monte Carlo met hod for mathematical modeling of light - tissue interaction . Monte Carlo is the statistical analysis of random sampling from the probability distributions used for tracking the photon movements inside the biological tissues. Various tissue models are created , and its fluence rates are analyzed . Furthermore, Monte Carlo method is developed for sa mpling and modeling of Gaussian beam on the multi - layered tissue. The absorption and fluence spectra have been analyzed for different types of Gaussian beam. Finally, comparison of beam profiles at different beam radius has been done .

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IITH Creators:
IITH CreatorsORCiD
Item Type: Thesis (Masters)
Uncontrolled Keywords: OCT, FFoCT, Monte carlo, TD702
Subjects: Biomedical Engineering
Divisions: Department of Biomedical Engineering
Depositing User: Team Library
Date Deposited: 02 Sep 2016 06:41
Last Modified: 20 Jun 2017 11:36
URI: http://raiith.iith.ac.in/id/eprint/2719
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