Domino [Pd]-Catalysis: One-pot Synthesis of Isobenzofuran-1(3H)-ones

Lodi, M and G, Satyanarayana (2016) Domino [Pd]-Catalysis: One-pot Synthesis of Isobenzofuran-1(3H)-ones. Journal of Organic Chemistry, 81 (17). pp. 7685-7691. ISSN 0022-3263

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An efficient domino [Pd]-catalysis for the synthesis of isobenzofuran-1(3H)-ones, is presented. The strategy showed broad substrate scope and amenable to ortho-bromobenzyl tertiary/secondary/primary alcohols. Significantly, the method was applied to the synthesis of anti-platelet drug n-butyl phthalide and cytotoxic agonist 3a-[4’-methoxylbenzyl]-5,7-dimethoxyphthalide.

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IITH Creators:
IITH CreatorsORCiD
G, SatyanarayanaUNSPECIFIED
Item Type: Article
Subjects: Chemistry > Organic chemistry
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Divisions: Department of Chemistry
Depositing User: Team Library
Date Deposited: 16 Aug 2016 08:40
Last Modified: 03 Oct 2016 06:08
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