Transition-Metal-Free Direct C(sp3)-H Functionalization leading to Aza-γ-Carboline Alkaloid Analogues in Cascade Fashion

Ghosh, Ruma (2016) Transition-Metal-Free Direct C(sp3)-H Functionalization leading to Aza-γ-Carboline Alkaloid Analogues in Cascade Fashion. Masters thesis, Indian Institute of Technology Hyderabad.

[img] Text
CY14MSCST11015.pdf - Submitted Version
Restricted to Registered users only until 3 May 2019.

Download (2MB) | Request a copy

Abstract

Iodine promoted cascade reaction has been developed for the synthesis of unrivalled Aza-γ-carboline alkaloid analogues via C-H functionalization of 2H-indazoles. The construction of the product has been realized under metal-free condition via in situ formation of imine, transimination followed by cyclization. In this present method iodine played a triple role, in imine formation, transimination and imine activation. The key features of the present protocol are metal-free, peroxide-free, operational simplicity and wide substrates scope.

[error in script]
IITH Creators:
IITH CreatorsORCiD
Item Type: Thesis (Masters)
Uncontrolled Keywords: Transition-metal free, Evironmentally friendly, Molecular iodine, TD503
Subjects: ?? sub5.8 ??
Divisions: Department of Chemistry
Depositing User: Library Staff
Date Deposited: 05 May 2016 05:07
Last Modified: 05 May 2016 05:07
URI: http://raiith.iith.ac.in/id/eprint/2316
Publisher URL:
Related URLs:

Actions (login required)

View Item View Item
Statistics for RAIITH ePrint 2316 Statistics for this ePrint Item