Pulsatile flow of blood through a 2D double-stenosed channel: effect of stenosis and pulsatility on wall shear stress

N, Nandakumar and Mohan, Anand (2016) Pulsatile flow of blood through a 2D double-stenosed channel: effect of stenosis and pulsatility on wall shear stress. International Journal of Advances in Engineering Sciences and Applied Mathematics, 8 (1). pp. 61-69. ISSN 0975-0770

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Abstract

Numerical simulations are performed for two-dimensional steady and pulsatile flow of blood through a channel with single as well as double stenosis (with varying gap) under aortic conditions (Re = 4000). A shear-thinning model based on experimental data is used for blood. The governing equations are developed in terms of vorticity and stream function and solved using a finite difference scheme with full-multigrid algorithm. Peak wall shear stress increases with both length of stenosis, and gap between stenosis; however, the effect of increasing length is much more compared to gap. Pulsatility plays a key role by shifting the location of peak wall shear stress from the primary to the secondary stenosis, and back again, during a cycle. This result is of importance when developing a model for plaque growth based purely on mechanical factors.

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IITH Creators:
IITH CreatorsORCiD
Mohan, Anandhttps://orcid.org/0000-0001-7191-4991
Item Type: Article
Uncontrolled Keywords: Blood, Yeleswarapu model, Multiple stenosis, Pulsatile flow, Wall shear stress
Subjects: Chemical Engineering > Biochemical Engineering
Divisions: Department of Chemical Engineering
Depositing User: Team Library
Date Deposited: 08 Mar 2016 06:43
Last Modified: 05 Dec 2017 05:30
URI: http://raiith.iith.ac.in/id/eprint/2233
Publisher URL: http://dx.doi.org/10.1007/s12572-016-0165-2
OA policy: http://www.sherpa.ac.uk/romeo/issn/0975-0770/
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