Self assembled nanocages from DNA-protoporphyrin hybrid molecules

Singh, V and Monisha, M and Roy, Anindya and Das, P (2015) Self assembled nanocages from DNA-protoporphyrin hybrid molecules. RSC Advances, 5 (108). pp. 89025-89029. ISSN 2046-2069

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Abstract

DNA-organic hybrid molecular building blocks are generated by covalent conjugation of the carboxyl groups of protoporphyrin IX with the amine functional groups of modified DNA oligomers. The hybrids are used to engineer DNA nanocages by self-assembly of the complementary DNA-organic molecule conjugates. The nanocages were found to be lined up in head to tail fashion under the selective ionic strength of the solution. Computational approach revealed the area and volume acquired by each DNA-organic hybrid nanocages.

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IITH Creators:
IITH CreatorsORCiD
Roy, Anindyahttp://orcid.org/0000-0001-8561-907X
Item Type: Article
Additional Information: IIT Patna is acknowledged for providing infrastructural and experimental facilities.
Uncontrolled Keywords: Ionic strength; Molecules; Self assembly Amine functional groups; Carboxyl groups; Computational approach; Hybrid molecules; Molecular building blocks; Organic molecules; Protoporphyrin IX; Protoporphyrins
Subjects: Others > Biotechnology
Divisions: Department of Biotechnology
Depositing User: Team Library
Date Deposited: 12 Nov 2015 07:20
Last Modified: 05 Dec 2017 04:52
URI: http://raiith.iith.ac.in/id/eprint/2015
Publisher URL: https://doi.org/10.1039/C5RA16851A
OA policy: http://www.sherpa.ac.uk/romeo/issn/2046-2069/
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