Domino One-Pot Process for the Synthesis of Isobenzofuran-1(3H)-ones via [Cu]-Catalysis Using Water as the Green Solvent

Lodi, M and G, Satyanarayana (2015) Domino One-Pot Process for the Synthesis of Isobenzofuran-1(3H)-ones via [Cu]-Catalysis Using Water as the Green Solvent. Journal of Organic Chemistry, 80 (14). pp. 7089-7098. ISSN 0022-3263

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Abstract

An efficient domino one-pot strategy via [Cu]-catalyzed intermolecular “cyanation” of o-bromobenzyl alcohols → in situ intramolecular “nucleophilic attack” → “hydrolysis” is presented, for the synthesis of isobenzofuran-1(3H)-ones. Significantly, the reaction is successfully carried out under environmentally benign conditions, using water as sole green solvent.

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IITH Creators:
IITH CreatorsORCiD
G, SatyanarayanaUNSPECIFIED
Item Type: Article
Subjects: Chemistry > Organic chemistry
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Divisions: Department of Chemistry
Depositing User: Team Library
Date Deposited: 11 Aug 2015 06:19
Last Modified: 24 Sep 2015 10:19
URI: http://raiith.iith.ac.in/id/eprint/1838
Publisher URL: http://dx.doi.org/10.1021/acs.joc.5b00888
OA policy: http://www.sherpa.ac.uk/romeo/issn/0022-3263/
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