Fabrication and surface functionalization of electrospun polystyrene submicron fibers with controllable surface roughness

Haridas, A K and Sharma, C S and V, Sritharan and Rao, T N (2014) Fabrication and surface functionalization of electrospun polystyrene submicron fibers with controllable surface roughness. RSC Advances (4). pp. 12188-12197. ISSN 2046-2069

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Abstract

Polystyrene (PS) submicron fibers of 14 wt% concentration were fabricated by electrospinning using dimethylformamide (DMF)–tetrahydrofuran (THF) solvent system. The surface morphology of PS fibers was modified from smooth to rough by changing the mixing ratio of DMF and THF in the spinning solution. The electrospun PS fibers with smooth and rough surfaces were then amidomethylated by treating with N-hydroxymethyl-2-chloroacetamide. PS fibers with higher roughness incorporated more amidomethyl functional groups on their surface, as confirmed by XPS analysis. This observation was further supported by BET adsorption isotherm results which showed a significant increase in specific surface area of rough PS electrospun fibers. Interestingly, amidomethylation has altered rough electrospun PS submicron fibers from extremely hydrophobic to hydrophilic. These chemically modified electrospun PS fibers with controllable surface roughness and wettability may be utilized as a carrier for proteins, mainly enzymes and antibodies, by covalent linkage through amino groups attached to their surface.

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IITH Creators:
IITH CreatorsORCiD
Sharma, C SUNSPECIFIED
Item Type: Article
Additional Information: We acknowledge Mr Venkatesh and Dr Neha Hebalkar of ARCI, for their assistance in FESEM imaging and XPS study. We are thankful to Dr V. V. S. S. Srikanth and Mr Kuntumalla Mohan Kumar of University of Hyderabad, India, for AFM imaging.
Subjects: Chemical Engineering > Biochemical Engineering
Divisions: Department of Chemical Engineering
Depositing User: Team Library
Date Deposited: 17 Mar 2015 09:30
Last Modified: 17 Mar 2015 09:30
URI: http://raiith.iith.ac.in/id/eprint/1406
Publisher URL: http://dx.doi.org/10.1039/C3RA44170A
OA policy: http://www.sherpa.ac.uk/romeo/issn/2046-2069/
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